Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813025 | 0.88 | MEN1 (0.58) | CTSVCTSLMEN1KMT2AKDM4E | |
| SCHEMBL27971948 | 0.85 | CTSV (0.51) | CTSVCTSLMEN1KMT2AKDM4E | |
| SCHEMBL8834058 | 0.78 | AKR1C3 (0.56) | CTSVCTSLMEN1KMT2AKDM4E | |
| SCHEMBL1438926 | 0.77 | PKM (0.62) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL11541393 | 0.77 | HTT (0.54) | KMT2AKDM4EHSD17B10HPGDAKR1C3 | |
| SCHEMBL20745310 | 0.77 | KDM4E (0.71) | CTSVCTSLMEN1KMT2AKDM4E | |
| SCHEMBL4336350 | 0.77 | KDM4E (0.59) | CTSVCTSLMEN1KMT2AKDM4E | |
| SCHEMBL26106266 | 0.74 | MEN1 (0.57) | CTSVCTSLMEN1KMT2AKDM4E | |
| SCHEMBL19260548 | 0.73 | AKR1C3 (0.61) | CTSVCTSLMEN1KMT2AKDM4E | |
| SCHEMBL16784742 | 0.73 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923007-B | Acridine compound and application thereof | 大连理工大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-103923007-A | Acridine compound and application thereof | UNIV DALIAN TECH | 2014-07-16 | — | — | CN | disclosed |