Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27972740

N.O=C1C=C(c2cccc(Br)c2Br)C(=O)N1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.39
CSNK1A1 P48729 1/20 0.39
CDK5 Q00535 1/20 0.39
ROCK1 Q13464 1/20 0.39
DYRK1A Q13627 1/20 0.39
LRRK2 Q5S007 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
PARP10 Q53GL7 1/20 0.37
PARP11 Q9NR21 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
GSK3B P49841 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6046984 0.98 PIM1 (0.40) PIM1CSNK1A1CDK5ROCK1DYRK1A
SCHEMBL6046967 0.84 GSK3B (0.41) PIM1CSNK1A1CDK5ROCK1DYRK1A
SCHEMBL331536 0.82 TDP2 (0.32)
SCHEMBL1050913 0.77 GSK3B (0.41) PIM1CDK5LRRK2DYRK1BGSK3B
SCHEMBL121405 0.77 GSK3B (0.50) LRRK2DYRK1BCA1CA2CA7
SCHEMBL27664385 0.77 GSK3B (0.50) LRRK2DYRK1BCA1CA2CA7
SCHEMBL11120799 0.75 GSK3B (0.48) LRRK2DYRK1BCA1CA2CA7
SCHEMBL8847907 0.74 DAO (0.40) LRRK2DYRK1BPARP10PARP11CA1
SCHEMBL5879280 0.73 CYP2A6 (0.45) PIM1CDK5PARP1
SCHEMBL5879217 0.73 CLK1 (0.43) PIM1CDK5DYRK1AGSK3BPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109320890-A Rubber-modified styrene resin composition, process for producing the same, and molded article 奇美实业股份有限公司 2019-02-12 CN disclosed
CN-106188926-B Rubber modified polystyrene resin and preparation method thereof 奇美实业股份有限公司 2018-10-02 CN disclosed
CN-108264723-A Rubber modified styrene resin composition and formed product thereof 奇美实业股份有限公司 2018-07-10 CN disclosed
CN-106867128-A Thermoplastic resin composition and molded article formed therefrom 奇美实业股份有限公司 2017-06-20 CN disclosed
CN-106188926-A Rubber modified polystyrene resin and preparation method thereof 奇美实业股份有限公司 2016-12-07 CN disclosed
CN-103897281-B Thermoplastic resin composition and molded article CHI MEI CORP. (CN) 2016-05-11 CN disclosed
CN-103897281-A Thermoplastic resin composition and molded article CHIMEI IND COMPANY 2014-07-02 CN disclosed