SCHEMBL6046984

SCHEMBL6046984

O=C1C=C(c2cccc(Br)c2Br)C(=O)N1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.40
CSNK1A1 P48729 1/20 0.40
CDK5 Q00535 1/20 0.40
ROCK1 Q13464 1/20 0.40
DYRK1A Q13627 1/20 0.40
LRRK2 Q5S007 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
PARP10 Q53GL7 1/20 0.38
PARP11 Q9NR21 1/20 0.38
CA9 Q16790 3/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
GSK3B P49841 1/20 0.34
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
PARP1 P09874 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CASP3 P42574 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27972740 0.98 PIM1 (0.39) PIM1CSNK1A1CDK5ROCK1DYRK1A
SCHEMBL6046967 0.85 GSK3B (0.41) PIM1CSNK1A1CDK5ROCK1DYRK1A
SCHEMBL331536 0.84 TDP2 (0.32)
SCHEMBL1050913 0.79 GSK3B (0.41) PIM1CDK5LRRK2DYRK1BGSK3B
SCHEMBL27664385 0.78 GSK3B (0.50) LRRK2DYRK1BCA9CA1CA2
SCHEMBL121405 0.78 GSK3B (0.50) LRRK2DYRK1BCA9CA1CA2
SCHEMBL11120799 0.77 GSK3B (0.48) LRRK2DYRK1BCA9CA1CA2
SCHEMBL8847907 0.76 DAO (0.40) LRRK2DYRK1BPARP10PARP11CA9
SCHEMBL5879280 0.74 CYP2A6 (0.45) PIM1CDK5PARP1
SCHEMBL5879217 0.74 CLK1 (0.43) PIM1CDK5DYRK1AGSK3BPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118599234-A Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2024-09-06 CN disclosed
CN-115087702-B Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2024-05-31 CN disclosed
US-20230099634-A1 STYRENE-BASED RESIN COMPOSITION, FLAME RETARDANT STYRENE-BASED RESIN COMPOSITION, MOLDED BODY, AND PATCH ANTENNA PS JAPAN CORPORATION (JP) 2023-03-30 US disclosed
CN-115087702-A Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2022-09-20 CN disclosed
US-20060292450-A1 Non-aqueous electrolyte secondary battery MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. 2006-12-28 US disclosed
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed