Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | YES1 | P07947 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27514694 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KMT2ASMN1; SMN2MAPTFNTA | |
| SCHEMBL27770330 | 0.84 | CHRM1 (0.43) | LMNA | |
| SCHEMBL27514034 | 0.81 | FNTA (0.35) | ALDH1A1KMT2ASMN1; SMN2MAPTFNTA | |
| SCHEMBL27730180 | 0.78 | CNR2 (0.45) | ALDH1A1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL28818119 | 0.74 | KDM4E (0.34) | ALDH1A1KMT2AMAPTLMNAIDO1 | |
| SCHEMBL28035914 | 0.74 | KMT2A (0.33) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL27729558 | 0.72 | PDE4A (0.37) | ALDH1A1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL27926249 | 0.72 | PTPN1 (0.34) | ALDH1A1 | |
| SCHEMBL28760252 | 0.72 | LMNA (0.31) | ALDH1A1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL28851874 | 0.72 | MEN1 (0.41) | ALDH1A1KMT2ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958472-A | Aryl-or N-heteroaryl-substituted methanesulfonamide derivatives as vanilloid receptor ligands | GRUENENTHAL GMBH | 2014-07-30 | — | — | CN | disclosed |