Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293268 | 0.84 | SMN1; SMN2 (0.43) | POLBALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL2514163 | 0.80 | MAPK1 (0.56) | ALDH1A1SMN1; SMN2LMNACYP1A2MAPK1 | |
| SCHEMBL28872888 | 0.77 | KCNJ6 (0.44) | SMN1; SMN2LMNAMAPK1RAB9AMAPT | |
| SCHEMBL28293385 | 0.77 | POLB (0.55) | POLBALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL28872885 | 0.75 | LMNA (0.60) | POLBALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL28295432 | 0.75 | GAA (0.55) | POLBALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL12918496 | 0.74 | POLB (0.64) | POLBALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL27868556 | 0.74 | GAA (0.56) | POLBALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL28295435 | 0.74 | POLB (0.43) | POLBALDH1A1LMNACYP1A2MAPK1 | |
| SCHEMBL27868554 | 0.73 | MAPT (0.38) | POLBALDH1A1SMN1; SMN2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293551-A | Method and composition relevant to granulocyte colony stimulating factor receptor | 利亘制药公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-104039761-A | Methods and compositions related to granulocyte colony stimulating factor receptor | LIGAND PHARM INC | 2014-09-10 | — | — | CN | disclosed |