Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichlorobenzene SCHEMBL27901773 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1TSHRKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5702222 | 0.77 | KMT2A (0.54) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL197298 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL27973581 | 0.75 | LMNA (0.59) | ALDH1A1TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10751878 | 0.71 | MAPT (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL14842963 | 0.71 | KMT2A (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL27968857 | 0.71 | TSHR (0.58) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL27747787 | 0.71 | HPGD (0.69) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL7560964 | 0.71 | CA12 (0.54) | ALDH1A1TSHRSMN1; SMN2RAB9ALMNA | |
| SCHEMBL2399695 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039152-A | Antibacterial compounds | GLAXO GROUP LTD | 2014-09-10 | — | — | CN | disclosed |