Phosphoric Acid

Phosphoric Acid

SCHEMBL27973641

CCCCC(CC)Cc1ccc(C)cc1.O=P(O)(O)O

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
GLA P06280 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
CYP3A4 P08684 2/20 0.40
ALDH1A1 P00352 2/20 0.39
CA2 P00918 2/20 0.39
HPGD P15428 1/20 0.39
FDPS P14324 1/20 0.38
ENPP2 Q13822 1/20 0.37
S1PR1 P21453 2/20 0.37
S1PR3 Q99500 2/20 0.37
S1PR2 O95136 1/20 0.37
S1PR4 O95977 1/20 0.37
BDKRB2 P30411 1/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033135 0.90 BDKRB2 (0.43) L3MBTL1GLATSHRHTTCYP3A4
SCHEMBL20183979 0.84 L3MBTL1 (0.41) L3MBTL1GLATSHRHTTCYP3A4
SCHEMBL153634 0.83 BDKRB2 (0.48) L3MBTL1GLATSHRHTTCYP3A4
Phosphoric Acid SCHEMBL15475371 0.81 TSHR (0.37) L3MBTL1GLATSHRHTTCYP3A4
SCHEMBL5936017 0.81 BLM (0.45) L3MBTL1CYP3A4ALDH1A1CA2S1PR1
SCHEMBL9807562 0.81 CYP2C19 (0.42) L3MBTL1GLATSHRHTTCYP3A4
Formic Acid SCHEMBL28247722 0.80 ALDH1A1 (0.44) L3MBTL1GLATSHRHTTCYP3A4
SCHEMBL105942 0.78 ESR1 (0.51) CYP3A4ALDH1A1CA2BDKRB2LMNA
SCHEMBL27898397 0.78 ALDH1A1 (0.50) L3MBTL1GLATSHRHTTCYP3A4
SCHEMBL3419642 0.78 BDKRB2 (0.42) L3MBTL1GLATSHRHTTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104053302-A Dielectric materials, methods of forming subassemblies therefrom, and subassemblies formed therewith ROGERS CORP 2014-09-17 CN disclosed
CN-102481598-B Dielectric material, method of forming a subassembly therefrom, and subassembly formed thereby ROGERS CORP 2014-07-09 CN disclosed