SCHEMBL27974366

SCHEMBL27974366

COS(=O)(=O)S(=O)(=O)O.N/N=C/c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.38
MAPT P10636 2/20 0.33
EGFR P00533 1/20 0.33
MET P08581 1/20 0.33
ROS1 P08922 1/20 0.33
ALK Q9UM73 1/20 0.33
GAA P10253 2/20 0.33
GCGR P47871 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
MITF O75030 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
BCHE P06276 2/20 0.33
ACHE P22303 2/20 0.33
BACE1 P56817 1/20 0.33
LIPE Q05469 1/20 0.32
NPY5R Q15761 1/20 0.32
MCHR1 Q99705 1/20 0.32
CA12 O43570 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10006369 0.88 PTGS2 (0.38) PTGS2MAPTGAAMEN1NPC1
SCHEMBL10006366 0.88 PTGS2 (0.38) PTGS2MAPTGAAMEN1NPC1
SCHEMBL27860065 0.85 PTGS2 (0.36) PTGS2MAPTGAAMEN1NPC1
SCHEMBL21052722 0.80 KMT2A (0.37) PTGS2MAPTGAAMEN1NPC1
SCHEMBL11915479 0.78 SCN5A (0.37) PTGS2MAPTGAABCHEACHE
SCHEMBL716281 0.78 KDM4E (0.39) PTGS2MAPTGAABCHEACHE
SCHEMBL18114755 0.77 PTGS2 (0.38) PTGS2MAPTGAABCHEACHE
SCHEMBL27993504 0.76 GAA (0.40) PTGS2MAPTEGFRMETROS1
SCHEMBL28831549 0.76 LMNA (0.45) GAANPC1RAB9AKDM4E
SCHEMBL22173634 0.75 CHRNA7 (0.46) PTGS2MAPTGAAMCHR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102548410-B Pesticidal compositions DOW AGROSCIENCES LLC (US) 2014-10-22 CN disclosed