Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230714 | 0.90 | KCNJ1 (0.40) | KDM4EALDH1A1SMN1; SMN2KCNJ1PTGS2 | |
| SCHEMBL11915479 | 0.90 | SCN5A (0.37) | KDM4EPTGS2TDP2SCN5ABCHE | |
| SCHEMBL18114755 | 0.89 | PTGS2 (0.38) | KDM4EPTGS2TDP2SCN5ABCHE | |
| SCHEMBL16031017 | 0.89 | SCN5A (0.36) | KDM4EPTGS2TDP2SCN5ABCHE | |
| SCHEMBL21092209 | 0.86 | SCN5A (0.35) | KDM4EPTGS2TDP2SCN5ABCHE | |
| SCHEMBL10006366 | 0.85 | PTGS2 (0.38) | KDM4EPTGS2TDP2SCN5ABCHE | |
| SCHEMBL21092106 | 0.85 | CHRNA7 (0.39) | KDM4EALDH1A1SMN1; SMN2PTGS2MAPK1 | |
| SCHEMBL21052722 | 0.85 | KMT2A (0.37) | KDM4EALDH1A1PTGS2SCN5ABCHE | |
| SCHEMBL10006369 | 0.85 | PTGS2 (0.38) | KDM4EPTGS2TDP2SCN5ABCHE | |
| SCHEMBL16030289 | 0.85 | IP6K1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970176-B1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-111163638-B | Pesticidal compositions and methods | 美国陶氏益农公司 | 2023-07-25 | — | — | CN | disclosed |
| US-20230203026-A1 | PESTICIDAL COMPOSITIONS AND METHODS | CORTEVA AGRISCIENCE LLC (US) | 2023-06-29 | — | — | US | disclosed |
| US-20210380576-A1 | PESTICIDAL COMPOSITIONS AND METHODS | DOW AGROSCIENCES LLC (US) | 2021-12-09 | — | — | US | disclosed |
| CN-107573295-B | Molecules and intermediates having pesticidal utility, compositions and methods relating thereto | 美国陶氏益农公司 | 2020-12-15 | — | — | CN | disclosed |
| EP-3720281-A1 | PESTICIDAL COMPOSITIONS AND METHODS | Dow Agrosciences LLC (US) | 2020-10-14 | — | — | EP | disclosed |
| CN-111163638-A | Pesticidal compositions and methods | 美国陶氏益农公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-107105657-B | Molecules having pesticidal utility, and intermediates, compositions, and methods related thereto | 美国陶氏益农公司 | 2020-03-03 | — | — | CN | disclosed |
| WO-2019113006-A1 | PESTICIDAL COMPOSITIONS AND METHODS | DOW AGROSCIENCES LLC (US) | 2019-06-13 | — | — | WO | disclosed |
| EP-3232788-B1 | TRIAZOLES DERIVATIVES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-06-12 | — | — | EP | disclosed |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20120053216-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012027521-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011017504-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| EP-2247603-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009102736-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | KDM4E 706/4885ALDH1A1 2110/4885SMN1; SMN2 2594/4885 |
| US-20120053216-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PLA2G4C | KDM4E 2951/4885ALDH1A1 2432/4885SMN1; SMN2 2949/4885 |
| US-20230203026-A1 | PESTICIDAL COMPOSITIONS AND METHODS | ACHE, DDT, PLA2G2D | KDM4E 1659/4885ALDH1A1 762/4885SMN1; SMN2 2913/4885 |
| US-20210380576-A1 | PESTICIDAL COMPOSITIONS AND METHODS | ACHE, DDT, PLA2G2D | KDM4E 1659/4885ALDH1A1 762/4885SMN1; SMN2 2913/4885 |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDM4E 1172/4885ALDH1A1 2560/4885SMN1; SMN2 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.