Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975857 | 0.86 | MAPT (0.52) | APPMGAMGAASIMGAM2 | |
| SCHEMBL28036417 | 0.85 | ACHE (0.46) | APPMGAMGAASIMGAM2 | |
| SCHEMBL27975865 | 0.83 | TAAR1 (0.46) | LOXL2GAAMAPTALDH1A1MEN1 | |
| SCHEMBL28036418 | 0.76 | MAPT (0.39) | APPMGAMGAASIMGAM2 | |
| SCHEMBL354332 | 0.72 | LOXL2 (1.00) | LOXL2CA12CA1CA2CA9 | |
| SCHEMBL27975859 | 0.71 | ALDH1A1 (0.37) | GAAMAPTALDH1A1MEN1HTT | |
| SCHEMBL4687550 | 0.70 | LOXL2 (0.88) | LOXL2CA12CA1CA2CA9 | |
| Methane SCHEMBL11552193 | 0.70 | LOXL2 (0.95) | LOXL2CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL726 | 0.70 | LOXL2 (0.95) | LOXL2CA12CA1CA2CA9 | |
| Bromide SCHEMBL31513716 | 0.70 | LOXL2 (0.95) | LOXL2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980248-B | 3,5-bis-substituted-4-amino thiophene-2-formaldehyde compound and preparation method thereof | ZHEJIANG UNIVERSITY (CN) | 2015-11-18 | — | — | CN | disclosed |
| CN-103980248-A | 3,5-bisubstituted-4-aminothiophene-2-formaldehyde compound and preparation method thereof | UNIV ZHEJIANG | 2014-08-13 | — | — | CN | disclosed |