Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 3/20 | 0.48 |
| ▸ | SI | P14410 | 3/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975918 | 1.00 | TP53 (0.52) | TP53PPARGGAAMGAMSI | |
| SCHEMBL27975920 | 0.96 | TP53 (0.48) | TP53PPARGGAAMGAMSI | |
| SCHEMBL28096950 | 0.95 | PPARG (0.51) | TP53PPARGGAAMGAMSI | |
| SCHEMBL28096774 | 0.87 | HTT (0.45) | TP53PPARGGAAMGAMSI | |
| SCHEMBL27976295 | 0.83 | GAA (0.46) | PPARGGAAMGAMSIMGAM2 | |
| Trifluoroacetic Acid SCHEMBL8798382 | 0.74 | ALDH1A1 (0.54) | TP53GAAMGAMSIMGAM2 | |
| SCHEMBL8798390 | 0.74 | ALDH1A1 (0.54) | TP53GAAMGAMSIMGAM2 | |
| SCHEMBL8393562 | 0.74 | SMN1; SMN2 (0.73) | TP53PPARGGAASMN1; SMN2HTT | |
| SCHEMBL8823088 | 0.74 | HTT (0.48) | TP53PPARGGAASMN1; SMN2HTT | |
| SCHEMBL17955990 | 0.74 | RXRA (0.48) | GAAMGAMSIMGAM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992276-A | 4'-{[(2,4,5-trisubstituted phenyl)-1H-imidazole-1-yl]methyl}biphenyl-2-formic acid derivatives | JILIN INST OF PHARMACEUTICAL RES | 2014-08-20 | — | — | CN | disclosed |