Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975918 | 0.95 | TP53 (0.52) | PPARGSMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL27975917 | 0.95 | TP53 (0.52) | PPARGSMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL28096774 | 0.92 | HTT (0.45) | PPARGSMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL27975920 | 0.91 | TP53 (0.48) | PPARGSMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL27976295 | 0.87 | GAA (0.46) | PPARGSMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL17955990 | 0.77 | RXRA (0.48) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL8798390 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2HTTALDH1A1KDM4ELMNA | |
| Trifluoroacetic Acid SCHEMBL8798382 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2HTTALDH1A1KDM4ELMNA | |
| SCHEMBL8393562 | 0.76 | SMN1; SMN2 (0.73) | PPARGSMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL17956034 | 0.74 | NPC1 (0.48) | SMN1; SMN2HTTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992276-B | 4 '-{ [(2,4,5-tri-substituted phenyl)-1H-imidazoles-1-base] methyl } biphenyl-2-formic acid derivates | 吉林省药物研究院 | 2016-08-24 | — | — | CN | disclosed |