Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.91 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.91 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.91 |
| ▸ | RELA | Q04206 | 1/20 | 0.91 |
| ▸ | MAOB | P27338 | 7/20 | 0.80 |
| ▸ | MAPT | P10636 | 5/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.80 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.80 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.80 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.80 |
| ▸ | F3 | P13726 | 2/20 | 0.77 |
| ▸ | XDH | P47989 | 2/20 | 0.73 |
| ▸ | MAOA | P21397 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | P4HB | P07237 | 1/20 | 0.68 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10017455 | 1.00 | BCHE (0.91) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4-Methoxy Chalcone SCHEMBL521906 | 0.95 | BCHE (1.00) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4-Methoxy Chalcone SCHEMBL1566431 | 0.95 | BCHE (1.00) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4-Methoxy Chalcone SCHEMBL9338705 | 0.95 | BCHE (1.00) | BCHECYP3A4NFKB1NFKB2RELA | |
| SCHEMBL10017446 | 0.92 | BCHE (0.77) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4'-Methoxychalcone SCHEMBL3698831 | 0.91 | MAOB (0.97) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4'-Methoxychalcone SCHEMBL3698834 | 0.91 | MAOB (0.97) | BCHECYP3A4NFKB1NFKB2RELA | |
| SCHEMBL18972861 | 0.90 | BCHE (0.88) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4'-Methoxychalcone SCHEMBL1675978 | 0.89 | MAOB (1.00) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4'-Methoxychalcone SCHEMBL521905 | 0.89 | MAOB (1.00) | BCHECYP3A4NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992356-A | Michael addition product of ferrocene-based chalcone and ethyl acetoacetate and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2014-08-20 | — | — | CN | disclosed |