Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 1/20 | 1.00 |
| ▸ | RELA | Q04206 | 1/20 | 1.00 |
| ▸ | MAOB | P27338 | 8/20 | 0.88 |
| ▸ | MAPT | P10636 | 5/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.88 |
| ▸ | MEN1 | O00255 | 2/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.88 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.88 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.88 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.88 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.88 |
| ▸ | F3 | P13726 | 2/20 | 0.84 |
| ▸ | XDH | P47989 | 2/20 | 0.79 |
| ▸ | MAOA | P21397 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | P4HB | P07237 | 1/20 | 0.74 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methoxy Chalcone SCHEMBL521906 | 1.00 | BCHE (1.00) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4-Methoxy Chalcone SCHEMBL9338705 | 1.00 | BCHE (1.00) | BCHECYP3A4NFKB1NFKB2RELA | |
| SCHEMBL27977337 | 0.95 | BCHE (0.91) | BCHECYP3A4NFKB1NFKB2RELA | |
| SCHEMBL10017455 | 0.95 | BCHE (0.91) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4'-Methoxychalcone SCHEMBL3698831 | 0.95 | MAOB (0.97) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4'-Methoxychalcone SCHEMBL3698834 | 0.95 | MAOB (0.97) | BCHECYP3A4NFKB1NFKB2RELA | |
| SCHEMBL18972861 | 0.94 | BCHE (0.88) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4'-Methoxychalcone SCHEMBL1675978 | 0.93 | MAOB (1.00) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4'-Methoxychalcone SCHEMBL521905 | 0.93 | MAOB (1.00) | BCHECYP3A4NFKB1NFKB2RELA | |
| 4,4'-Dimethoxychalcone SCHEMBL978243 | 0.91 | F3 (1.00) | BCHECYP3A4NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384199-A | Preparation of novel organic aluminum hydrogen compound and preparation method of unsaturated alcohol compound catalyzed by novel organic aluminum hydrogen compound | 北京理工大学 | 2024-01-12 | — | — | CN | claimed |
| CN-113620901-B | Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof | 杭州师范大学 | 2023-02-10 | — | — | CN | claimed |
| CN-115141621-A | Oil-based fracturing fluid, multi-stage fracturing method and method for online monitoring productivity of reservoir intervals | 中国石油化工股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| US-20220003753-A1 | METABOLIC PROFILING FOR THE DIAGNOSIS OF A SUBSET OF IDIOPATHIC AUTISM SPECTRUM DISORDER PATIENTS, ADS PHENOTYPE 1 | STALICLA SA (CH) | 2022-01-06 | — | — | US | claimed |
| US-20210401728-A1 | Topical Compositions and Methods to Promote Optimal Dermal White Adipose Tissue Composition in Vivo | GALANIN IVAN (US) | 2021-12-30 | — | — | US | claimed |
| EP-3877540-A1 | METABOLIC PROFILING FOR THE DIAGNOSIS OF A SUBSET OF IDIOPATHIC AUTISM SPECTRUM DISORDER PATIENTS, ASD PHENOTYPE 1 | Stalicla S.A. (CH) | 2021-09-15 | — | — | EP | claimed |
| CN-113260423-A | Topical application composition and method for promoting optimal skin white adipose tissue composition in vivo | 伊万·加拉宁 | 2021-08-13 | — | — | CN | claimed |
| CN-113166811-A | Metabolic profiling for diagnosing subtype ASD phenotype 1 in patients with idiopathic autism spectrum disorders | 斯大利卡拉公司 | 2021-07-23 | — | — | CN | claimed |
| US-11040117-B2 | Treatment of a subtype of ASD | Stalicla S.A. (CH) | 2021-06-22 | — | — | US | claimed |
| US-20210169993-A1 | TREATMENT OF A SUBTYPE OF ASD | STALICLA SA (CH) | 2021-06-10 | — | — | US | claimed |
| EP-3706807-A1 | TREATMENT OF A SUBTYPE OF ASD | Stalicla S.A. (CH) | 2020-09-16 | — | — | EP | claimed |
| US-20190134152-A1 | TREATMENT OF A SUBTYPE OF ASD | Stalicla S.A. (CH) | 2019-05-09 | — | — | US | claimed |
| EP-1450777-B1 | PHARMACEUTICAL COMPOSITION CONTAINING CHALCONE OR ITS DERIVATIVES FOR MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY | ANGIOLAB INC (KR) | 2013-05-08 | — | — | EP | claimed |
| US-7572831-B2 | Composition containing chalcone | ANGIOLAB, INC. (KR) | 2009-08-11 | — | — | US | claimed |
| US-20040209952-A1 | Composition containing chalcone | ANGIOLAB, INC. (KR) | 2004-10-21 | — | — | US | claimed |
| EP-1450777-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CHALCONE OR ITS DERIVATIVES FOR MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY | Angiolab Inc. (KR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003037315-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CHALCONE OR ITS DERIVATIVES FOR MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY | ANGIOLAB INC. (KR) | 2003-05-08 | — | — | WO | claimed |
| JP-4202126-A | — | — | None | — | — | JP | disclosed |
| US-4067823-A | Thallium(III) reagents supported on montmorillonite clay minerals and oxythallation processes for utilizing same | EMERY INDUSTRIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |
| US-3983288-A | Fibers and fabrics containing optical brightening agents | EASTMAN KODAK COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209952-A1 | Composition containing chalcone | MMP25, MMP13, MMP17 | BCHE 501/4885CYP3A4 1458/4885NFKB1 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.