SCHEMBL10017446

SCHEMBL10017446

COc1ccc(-c2ccc(Cc3ccc(/C=C/C(=O)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.77
CYP3A4 P08684 1/20 0.77
NFKB1 P19838 1/20 0.77
NFKB2 Q00653 1/20 0.77
RELA Q04206 1/20 0.77
MAOB P27338 8/20 0.68
MAPT P10636 5/20 0.68
KMT2A Q03164 3/20 0.68
MEN1 O00255 2/20 0.68
ALDH1A1 P00352 2/20 0.68
CYP1B1 Q16678 2/20 0.68
HSPD1 P10809 1/20 0.68
TNFRSF1A P19438 1/20 0.68
HSPE1 P61604 1/20 0.68
F3 P13726 2/20 0.65
XDH P47989 2/20 0.63
RAB9A P51151 2/20 0.60
NPC1 O15118 2/20 0.60
MAOA P21397 3/20 0.59
P4HB P07237 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017461 0.96 BCHE (0.83) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL10017455 0.92 BCHE (0.91) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL27977337 0.92 BCHE (0.91) BCHECYP3A4NFKB1NFKB2RELA
4-Methoxy Chalcone SCHEMBL1566431 0.88 BCHE (1.00) BCHECYP3A4NFKB1NFKB2RELA
4-Methoxy Chalcone SCHEMBL9338705 0.88 BCHE (1.00) BCHECYP3A4NFKB1NFKB2RELA
4-Methoxy Chalcone SCHEMBL521906 0.88 BCHE (1.00) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL10017444 0.88 CYP3A4 (0.58) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL12062060 0.87 CYP3A4 (0.57) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL12062058 0.85 BCHE (0.58) BCHECYP3A4NFKB1NFKB2RELA
4'-Methoxychalcone SCHEMBL3698831 0.83 MAOB (0.97) BCHECYP3A4NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523889-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-12-20 US disclosed
US-9470929-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-10-18 US disclosed
US-9465244-B2 Liquid crystal display SONY CORPORATION (JP) 2016-10-11 US disclosed
US-9366910-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-06-14 US disclosed
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2016-01-14 US disclosed
US-9235084-B2 Liquid crystal display device and manufacturing method thereof SONY CORPORATION (JP) 2016-01-12 US disclosed
US-9146425-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2015-09-29 US disclosed
US-20150146148-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2015-05-28 US disclosed
US-9041887-B2 Liquid crystal display device and manufacturing method thereof SONY CORPORATION (JP) 2015-05-26 US disclosed
US-8993074-B2 Liquid crystal display device and method of manufacturing the same SONY CORPORATION (JP) 2015-03-31 US disclosed
US-20140307211-A1 LIQUID CRYSTAL DISPLAY SONY CORPORATION (JP) 2014-10-16 US disclosed
US-8830428-B2 Liquid crystal display element and liquid crystal display device SONY CORPORATION (JP) 2014-09-09 US disclosed
US-20140111752-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2014-04-24 US disclosed
US-20140071390-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2014-03-13 US disclosed
US-20130010244-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION 2013-01-10 US disclosed
US-20120212691-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-08-23 US disclosed
US-20120026440-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2012-02-02 US disclosed
US-20110273652-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-11-10 US disclosed
US-20110134382-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND LIQUID CRYSTAL DISPLAY DEVICE SONY CORPORATION (JP) 2011-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME PYM1, PDCD2L, SDAD1 BCHE 3203/4885CYP3A4 2921/4885NFKB1 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.