Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978471 | 1.00 | DRD2 (0.39) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL27978561 | 1.00 | DRD2 (0.39) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL28087471 | 0.87 | LTA4H (0.40) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL27978805 | 0.85 | SIGMAR1 (0.35) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL27978739 | 0.83 | DRD2 (0.35) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL27978798 | 0.80 | AR (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL27978742 | 0.77 | RORC (0.37) | — | |
| SCHEMBL27978469 | 0.77 | CHRM3 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL27978721 | 0.74 | FFAR4 (0.35) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL14965307 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011054-A | Thieno- and furo-pyrimidines and pyridines, useful as potassium channel inhibitors | XENTION LTD | 2014-08-27 | — | — | CN | disclosed |