Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15018380 | 0.86 | KEAP1 (0.41) | KEAP1NFE2L2SCN9AMRGPRX4KDM4E | |
| SCHEMBL15543742 | 0.81 | KEAP1 (0.42) | KEAP1NFE2L2SCN9AMRGPRX4KDM4E | |
| SCHEMBL27979581 | 0.78 | KDM1A (0.31) | — | |
| SCHEMBL14331830 | 0.76 | KEAP1 (0.50) | KEAP1NFE2L2MRGPRX4KDM4EASPH | |
| SCHEMBL363365 | 0.74 | KEAP1 (0.48) | KEAP1NFE2L2MRGPRX4KDM4EASPH | |
| SCHEMBL29488312 | 0.74 | KEAP1 (0.48) | KEAP1NFE2L2MRGPRX4KDM4EASPH | |
| SCHEMBL18420388 | 0.73 | KDM4E (0.40) | KEAP1NFE2L2MRGPRX4KDM4EASPH | |
| SCHEMBL16618297 | 0.73 | KEAP1 (0.44) | KEAP1NFE2L2MRGPRX4KDM4EASPH | |
| SCHEMBL28353593 | 0.72 | HMGB1 (0.37) | KDM4EALDH1A1TSHRHPGDHSD17B10 | |
| SCHEMBL16387317 | 0.71 | DGAT1 (0.43) | SCN9AALDH1A1CASP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104718188-A | N-substituted benzamides and their use in the treatment of pain | GENENTECH INC | 2015-06-17 | — | — | CN | disclosed |