Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376754 | 0.84 | RAD52 (0.41) | THRBTYRCYP3A4HCAR2AKR1B10 | |
| SCHEMBL27981237 | 0.81 | TDP1 (0.53) | LMNATYRSMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL28040122 | 0.79 | AKR1B10 (0.44) | THRBSMN1; SMN2KDM4EHCAR2AKR1B10 | |
| SCHEMBL2404989 | 0.77 | ALDH1A1 (0.40) | THRBSMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL13873296 | 0.76 | LMNA (0.51) | LMNATYRSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL21596736 | 0.76 | LMNA (0.51) | LMNATYRSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL28561113 | 0.76 | TYR (0.59) | LMNATYRSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL11688548 | 0.76 | ALDH1A1 (0.40) | LMNASMN1; SMN2CYP1A2KDM4EALDH1A1 | |
| SCHEMBL28342445 | 0.75 | LMNA (0.41) | LMNANPSR1KDM4EALDH1A1RAB9A | |
| SCHEMBL2548713 | 0.75 | TAAR1 (0.50) | LMNATYRSMN1; SMN2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |