Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CFB | P00751 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984492 | 0.96 | SMN1; SMN2 (0.48) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11512490 | 0.86 | MEN1 (0.48) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL2789419 | 0.86 | KMT2A (0.52) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6242317 | 0.86 | CFB (0.48) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6092369 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL28945745 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8303313 | 0.81 | TMEM97 (0.58) | TMEM97SIGMAR1BRD4RIPK1MAOA | |
| SCHEMBL26984487 | 0.81 | TMEM97 (0.58) | TMEM97SIGMAR1BRD4RIPK1MAOA | |
| Hydrochloric Acid SCHEMBL12480511 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10775133 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011043-B | The quinuclidine esters of 1-aza heterocycles guanidine-acetic acid, their preparation method and Pharmaceutical composition thereof as muscarine antagonist | 奇斯药制品公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-104011043-A | Quinuclidine esters of 1-azaheterocyclylacetic acid as antimuscarinic agents, process for their preparation and medicinal compositions thereof | CHIESI FARMA SPA | 2014-08-27 | — | — | CN | disclosed |