Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984492 | 0.90 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL27984087 | 0.86 | KDM4E (0.50) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11511516 | 0.85 | FFAR1 (0.52) | MEN1KMT2AALDH1A1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL11510326 | 0.84 | FFAR1 (0.51) | MEN1KMT2AALDH1A1OPRK1OPRM1 | |
| SCHEMBL11511335 | 0.82 | CHRNB2 (0.49) | MEN1KMT2AALDH1A1OPRK1OPRM1 | |
| SCHEMBL11510335 | 0.80 | FFAR1 (0.54) | MEN1KMT2AOPRK1OPRM1HPGD | |
| SCHEMBL6242317 | 0.78 | CFB (0.48) | MEN1KMT2AALDH1A1OPRK1OPRM1 | |
| SCHEMBL11509496 | 0.78 | OPRK1 (0.62) | MEN1KMT2AALDH1A1OPRK1OPRM1 | |
| SCHEMBL11509424 | 0.77 | CHRNB2 (0.46) | MEN1KMT2AALDH1A1OPRK1OPRM1 | |
| SCHEMBL11510126 | 0.76 | RIPK1 (0.56) | ALDH1A1FFAR1NPC1RAB9ARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | disclosed |