Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367070 | 0.88 | KDM4E (0.46) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL28836843 | 0.86 | OPRK1 (0.55) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27984494 | 0.86 | OPRM1 (0.42) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL27984087 | 0.86 | KDM4E (0.50) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL27984090 | 0.84 | RIPK1 (0.52) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL6092369 | 0.83 | KDM4E (0.58) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL28945745 | 0.83 | KDM4E (0.58) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL10775133 | 0.82 | KDM4E (0.56) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL12480511 | 0.82 | KDM4E (0.56) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL10775129 | 0.82 | KDM4E (0.56) | KMT2AMEN1HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600952-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | MERCK SHARP & DOHME (GB) | 1994-06-15 | — | — | EP | claimed |
| WO-1993004040-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME LIMITED (GB) | 1993-03-04 | — | — | WO | claimed |
| CN-114929724-A | Human aminosterol ENT-03 compounds, related compositions comprising the same, and methods of use thereof | 因特尔公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2010144043-A1 | A NOVEL 4-METHYLBENZENESULPHONATE SALT AND A PROCESS FOR PREPARING A PHARMACEUTICAL COMPOSITION COMPRISING THE SALT | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | WO | disclosed |