Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984649 | 0.81 | THRA (0.41) | PPARDLTB4RLTB4R2MTNR1AMTNR1B | |
| SCHEMBL27984300 | 0.78 | MAPT (0.40) | L3MBTL1RAB9APOLBNPC1 | |
| SCHEMBL27984593 | 0.75 | HTR1D (0.43) | L3MBTL1RAB9APOLB | |
| SCHEMBL27984602 | 0.75 | HTR1D (0.43) | L3MBTL1RAB9APOLB | |
| SCHEMBL28050539 | 0.74 | HTR1A (0.44) | PPARDCTSLCTSSCTSKLTB4R | |
| SCHEMBL27764982 | 0.72 | KMT2A (0.40) | RAB9APOLBNPC1 | |
| SCHEMBL7335064 | 0.72 | PPARD (0.75) | PPARDLTB4RLTB4R2L3MBTL1 | |
| SCHEMBL28035599 | 0.71 | MAOB (0.47) | L3MBTL1 | |
| SCHEMBL2871402 | 0.71 | PPARD (0.58) | PPARDL3MBTL1RAB9ANPC1 | |
| SCHEMBL17398954 | 0.70 | THRA (0.55) | PPARDMTNR1AMTNR1BTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102007118-B | Pyrrolidinone glucokinase activators | HOFFMANN LA ROCHE | 2014-12-31 | — | — | CN | disclosed |