Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981683 | 0.83 | TTR (0.40) | KMT2AMEN1ALDH1A1ITGA4ITGB7 | |
| SCHEMBL6378448 | 0.80 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| Trifluoroacetic Acid SCHEMBL5982103 | 0.80 | TTR (0.38) | KMT2AMEN1ALDH1A1ITGA4ITGB7 | |
| SCHEMBL6378524 | 0.78 | VCAM1 (0.43) | KMT2AMEN1ALDH1A1MAPTVCAM1 | |
| SCHEMBL17258287 | 0.78 | ALDH1A1 (0.41) | ALDH1A1ITGA4ITGB7KDM4E | |
| SCHEMBL17258288 | 0.78 | ALDH1A1 (0.41) | ALDH1A1ITGA4ITGB7KDM4E | |
| SCHEMBL6948552 | 0.77 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTVCAM1 | |
| SCHEMBL11247732 | 0.77 | CASP6 (0.57) | KMT2AALDH1A1MAPTVCAM1CA12 | |
| SCHEMBL6655650 | 0.76 | KMT2A (0.43) | KMT2AMEN1ALDH1A1MAPTVCAM1 | |
| SCHEMBL31260597 | 0.75 | PDK1 (0.58) | KMT2AMEN1ALDH1A1MAPTVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482221-B | bicyclic and tricyclic compounds as KATII inhibitors | PFIZER INC. (US) | 2014-10-22 | — | — | CN | disclosed |