Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175829 | 0.76 | PDE2A (0.43) | FFAR4EPHX2 | |
| SCHEMBL27837804 | 0.76 | HSP90AB1 (0.60) | MAPTALDH1A1HPGDTSHRPDK1 | |
| SCHEMBL27986102 | 0.76 | EGLN1 (0.43) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL27462525 | 0.75 | HSP90AB1 (0.54) | MAPTALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL27719541 | 0.75 | THRB (0.45) | ALDH1A1KDM4EGAAKMT2AEPHX2 | |
| SCHEMBL12780426 | 0.74 | FFAR4 (0.44) | FFAR4EPHX2 | |
| SCHEMBL28783326 | 0.74 | HMGCR (0.45) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL28836960 | 0.73 | THRA (0.44) | FFAR4KDM4EGAAKMT2AEPHX2 | |
| SCHEMBL28841152 | 0.72 | FFAR4 (0.57) | MAPTFFAR4ALDH1A1HPGDKDM4E | |
| SCHEMBL11037115 | 0.71 | NPC1 (0.60) | MAPTALDH1A1HPGDTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245698-A | Nitrogen-containing heterocyclic compound | TAKEDA PHARMACEUTICAL | 2014-12-24 | — | — | CN | disclosed |