Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569082 | 0.80 | NPC1 (0.63) | MAPTALDH1A1HPGDTSHRNPC1 | |
| Hydrochloric Acid SCHEMBL10728839 | 0.78 | NPC1 (0.61) | MAPTALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL11037115 | 0.78 | NPC1 (0.60) | MAPTALDH1A1HPGDTSHRNPC1 | |
| Hydrochloric Acid SCHEMBL908553 | 0.75 | MAPT (0.63) | MAPTALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL27986113 | 0.75 | MAPT (0.47) | MAPTALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL27616180 | 0.75 | ALDH1A1 (0.51) | MAPTALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL10854322 | 0.73 | NPC1 (0.50) | MAPTALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL27581226 | 0.72 | HTT (0.51) | MAPTALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL3926124 | 0.71 | KMT2A (0.42) | MAPTALDH1A1HPGDNPC1MEN1 | |
| SCHEMBL17659019 | 0.71 | KMT2A (0.42) | MAPTALDH1A1HPGDNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159325-A | Co-therapy for Parkinson's syndrome | PFIZER (US) | 1997-09-17 | — | — | CN | disclosed |