Sugi Predict

Sugi Predict / Compounds / SCHEMBL2799262

SCHEMBL2799262

SCHEMBL2799262

Fc1ccc(C=C(CCl)c2cc(F)c(F)c(F)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ LMNA P02545 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ PTGS1 P23219 4/20 0.35
▸ PTGS2 P35354 2/20 0.35
▸ CES2 O00748 1/20 0.34
▸ CES1 P23141 1/20 0.34
▸ TRPA1 O75762 3/20 0.34
▸ ABCB11 O95342 1/20 0.34
▸ SIGMAR1 Q99720 1/20 0.34
▸ FBP1 P09467 1/20 0.33
▸ HDAC3 O15379 1/20 0.33
▸ HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2799258 1.00 MEN1 (0.37) MEN1KMT2ALMNACYP1A2MAPT
SCHEMBL3659671 0.85 ALDH1A1 (0.42) MEN1KMT2ALMNACYP1A2MAPT
SCHEMBL3779270 0.85 ALDH1A1 (0.42) MEN1KMT2ALMNACYP1A2MAPT
SCHEMBL2925552 0.79 PTGS1 (0.52) MEN1KMT2ALMNACYP1A2MAPT
SCHEMBL3765796 0.79 PTGS1 (0.52) MEN1KMT2ALMNACYP1A2MAPT
SCHEMBL3660987 0.77 ALDH1A1 (0.43) ALDH1A1HTTPTGS1PTGS2TRPA1
SCHEMBL2799013 0.77 MAPT (0.41) MEN1KMT2ALMNACYP1A2MAPT
SCHEMBL3777037 0.77 ALDH1A1 (0.43) ALDH1A1HTTPTGS1PTGS2TRPA1
SCHEMBL2799017 0.77 MAPT (0.41) MEN1KMT2ALMNACYP1A2MAPT
SCHEMBL3775608 0.75 NFE2L2 (0.38) MEN1KMT2ACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120225777-A1 Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them BASF SE (DE) 2012-09-06 — — US disclosed
US-20100317515-A1 Azolylmethyloxiranes, use Thereof and Agents Containing the Same BASF SE (DE) 2010-12-16 — — US disclosed
US-20100167924-A1 Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them BASF SE (DE) 2010-07-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100167924-A1 Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them PFAS, CBR3, CBR1 MEN1 2158/4885KMT2A 1371/4885LMNA 4009/4885
US-20100317515-A1 Azolylmethyloxiranes, use Thereof and Agents Containing the Same XDH, NOX5, TET1 MEN1 1724/4885KMT2A 490/4885LMNA 4209/4885
US-20120225777-A1 Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them PFAS, CBR3, CBR1 MEN1 2095/4885KMT2A 1397/4885LMNA 4009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.