SCHEMBL27993554

SCHEMBL27993554

CCCCCc1cccc2c(OC)c3ccccc3c(OC)c12

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.49
ALOX5 P09917 1/20 0.49
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PPARA Q07869 1/20 0.43
LIPG Q9Y5X9 1/20 0.42
MAPT P10636 1/20 0.40
POLB P06746 1/20 0.40
KCNH2 Q12809 1/20 0.39
TLR8 Q9NR97 4/20 0.38
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27664396 0.95 KDM4E (0.48) PTGS2ALOX5KDM4EALDH1A1MAPK1
SCHEMBL29288062 0.86 KDM4E (0.46) PTGS2ALOX5KDM4EALDH1A1MAPK1
SCHEMBL29367461 0.82 KDM4E (0.56) KDM4EALDH1A1MAPK1SMN1; SMN2MAPT
SCHEMBL2576344 0.82 KDM4E (0.56) KDM4EALDH1A1MAPK1SMN1; SMN2MAPT
SCHEMBL16741963 0.78 MPO (0.36) PTGS2ALOX5KDM4ESMN1; SMN2LIPG
SCHEMBL30849716 0.78 CSNK1A1 (0.40) PTGS2ALOX5LIPG
SCHEMBL2401301 0.78 CSNK1A1 (0.40) PTGS2ALOX5LIPG
SCHEMBL170762 0.78 LIPG (0.52) PTGS2ALOX5PPARALIPGKCNH2
SCHEMBL27664398 0.77 CSNK1A1 (0.37) PTGS2ALOX5KDM4ELIPG
SCHEMBL28434207 0.76 LIPG (0.55) PTGS2ALOX5PPARALIPGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104276997-A Novel anthracene derivatives containing electron-deficient aromatic ring, and preparation method and application thereof NANJING YOUSIBEITE PHOTOELECTRIC MATERIAL CO LTD 2015-01-14 CN claimed
CN-104276997-A Novel anthracene derivatives containing electron-deficient aromatic ring, and preparation method and application thereof NANJING YOUSIBEITE PHOTOELECTRIC MATERIAL CO LTD 2015-01-14 CN disclosed