Boric Acid

Boric Acid

SCHEMBL27995448

CCCCc1ccc(OC(C)(C)C(C)(C)O)cc1.OB(O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
LPL P06858 4/20 0.44
LIPG Q9Y5X9 4/20 0.44
PPARA Q07869 2/20 0.43
TRPV1 Q8NER1 1/20 0.42
MGLL Q99685 1/20 0.42
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
STS P08842 2/20 0.40
HSD17B10 Q99714 2/20 0.40
THRB P10828 2/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 3/20 0.39
MEN1 O00255 2/20 0.39
MAPK1 P28482 2/20 0.39
KMT2A Q03164 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Boric Acid SCHEMBL28317847 0.80 PPARG (0.53) PPARA
Boric Acid SCHEMBL27885570 0.79 KEAP1 (0.41) PPARAHTR2C
SCHEMBL5702512 0.78 PPARA (0.47) CA1CA2PPARAALDH1A1HPGD
SCHEMBL15194641 0.77 CA1 (0.56) CA1CA2LPLLIPGTRPV1
Boric Acid SCHEMBL28004935 0.76 LTA4H (0.49) CA1CA2PPARALMNAL3MBTL1
SCHEMBL28963297 0.76 ESR1 (0.55) LPLLIPGTRPV1MGLLALDH1A1
Butylbenzyl SCHEMBL27995238 0.75 CA1 (0.52) CA1CA2LPLLIPGTRPV1
Boric Acid SCHEMBL28801697 0.74 MEN1 (0.47) ALDH1A1HPGDHSD17B10LMNAMEN1
Boric Acid SCHEMBL28233693 0.74 ACHE (0.38) CA1CA2LPLLIPGPPARA
SCHEMBL6399912 0.73 CA1 (0.58) CA1CA2LPLLIPGTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104254518-A Linear peptide antibiotics RQX PHARMACEUTICALS INC 2014-12-31 CN disclosed