Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365910 | 0.80 | RECQL (0.64) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9526005 | 0.78 | RECQL (0.70) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL27256801 | 0.75 | RECQL (0.69) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9329215 | 0.74 | RECQL (1.00) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9690007 | 0.72 | RECQL (0.54) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9688818 | 0.72 | RECQL (0.66) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9688698 | 0.72 | RECQL (0.66) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8810190 | 0.70 | ALDH1A1 (0.51) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8807589 | 0.70 | RECQL (0.67) | RECQLMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8809336 | 0.70 | RECQL (0.57) | RECQLMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254109-B | Benzoyl pyrrole derivative and synthetic method thereof | UNIV SHANXI | 2015-01-28 | — | — | CN | disclosed |
| CN-103254109-A | Benzoyl pyrrole derivative and synthetic method thereof | UNIV SHANXI | 2013-08-21 | — | — | CN | disclosed |