Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810190 | 0.85 | ALDH1A1 (0.51) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL9688698 | 0.80 | RECQL (0.66) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL9688818 | 0.77 | RECQL (0.66) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL9690007 | 0.77 | RECQL (0.54) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL9688628 | 0.76 | ALDH1A1 (0.52) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL8807589 | 0.75 | RECQL (0.67) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL30543430 | 0.74 | RECQL (0.65) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL9526005 | 0.73 | RECQL (0.70) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL9329215 | 0.73 | RECQL (1.00) | RECQLLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL29489108 | 0.71 | RECQL (0.61) | RECQLLMNAMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791595-A1 | Methods for preparing 5-aroyl-1,2-dihydro-3h-pyrrolo-(1,2-a)Pyrrole-1-carboxylic acids | Ohmeda Pharmaceutical Products Division Inc. (US) | 1997-08-27 | — | — | EP | disclosed |