Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12005279 | 0.90 | MAPT (0.42) | DRD2DRD1DRD3ABCB1RAB9A | |
| SCHEMBL6245392 | 0.90 | ABCB1 (0.49) | DRD2DRD1DRD3ABCB1RAB9A | |
| SCHEMBL6246807 | 0.86 | DRD2 (0.53) | DRD2DRD1DRD3ABCB1LMNA | |
| SCHEMBL29518968 | 0.82 | DRD2 (0.59) | DRD2DRD1DRD3ABCB1RAB9A | |
| SCHEMBL18917587 | 0.82 | DRD2 (0.59) | DRD2DRD1DRD3ABCB1RAB9A | |
| SCHEMBL2796850 | 0.81 | L3MBTL1 (0.59) | RAB9ALMNAMAPTL3MBTL1ELANE | |
| SCHEMBL8673227 | 0.81 | LMNA (0.44) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL7252531 | 0.80 | LMNA (0.66) | DRD2DRD1DRD3ABCB1RAB9A | |
| Bicarbonate SCHEMBL28775865 | 0.80 | DRD2 (0.58) | DRD2DRD1DRD3ABCB1RAB9A | |
| SCHEMBL30444952 | 0.80 | DRD2 (0.61) | DRD2DRD1DRD3ABCB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750087-B2 | Modified polymers prepared with lanthanide-based catalysts | BRIDGESTONE CORPORATION (JP) | 2010-07-06 | — | — | US | claimed |