Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL27434751 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| Quinoline SCHEMBL27574374 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| Ether SCHEMBL16334360 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| Ethoxycarbonyl Group SCHEMBL27633949 | 0.79 | LMNA (0.40) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| Naphthalene SCHEMBL27488215 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| Ethoxycarbonyl Group SCHEMBL27884607 | 0.77 | MAPT (0.41) | ALDH1A1KDM4ELMNAKMT2AGAA | |
| Naphthalene SCHEMBL27634543 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| Ethoxycarbonyl Group SCHEMBL28048074 | 0.76 | ADRA2A (0.32) | KDM4ETSHRSMN1; SMN2MAPK1 | |
| Anthracene SCHEMBL27554619 | 0.75 | GAA (0.41) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| Formic Acid SCHEMBL27554937 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015651-B | Compounds and compositions as TLR activity modulators | IRM LLC | 2014-12-31 | — | — | CN | disclosed |