Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29983676 | 0.77 | PDK1 (0.39) | LMNAPOLBALDH1A1CYP3A4 | |
| SCHEMBL29984022 | 0.77 | PDK1 (0.39) | LMNAPOLBALDH1A1CYP3A4 | |
| SCHEMBL13642031 | 0.72 | HMGCR (0.36) | — | |
| SCHEMBL19301013 | 0.71 | CA2 (0.53) | LMNAPOLBALDH1A1 | |
| SCHEMBL11161746 | 0.71 | CA2 (0.41) | LMNAPOLBLPAR1LPAR3ENPP2 | |
| SCHEMBL2297204 | 0.71 | CA2 (0.49) | LMNAPOLBLPAR1LPAR3ENPP2 | |
| SCHEMBL14307904 | 0.71 | KCNH2 (0.38) | LMNAPOLBALDH1A1TSHR | |
| SCHEMBL17854689 | 0.70 | ALDH1A1 (0.46) | ALDH1A1LPAR1LPAR3CYP3A4TSHR | |
| SCHEMBL9080283 | 0.69 | CA2 (0.50) | LMNAPOLBLPAR1LPAR3 | |
| SCHEMBL21135532 | 0.69 | CA2 (0.50) | LMNAPOLBLPAR1LPAR3ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104293849-A | Preparation method of rosuvastatin calcium | CHANGZHOU JINLONG BIOLOG PHARMACEUTICAL CO LTD | 2015-01-21 | — | — | CN | disclosed |