Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997352 | 0.82 | ALDH1A1 (0.46) | GAAALDH1A1NPSR1KDM4EMEN1 | |
| SCHEMBL157423 | 0.79 | TSHR (0.37) | GAAL3MBTL1ALDH1A1TDP1NPSR1 | |
| SCHEMBL1444265 | 0.77 | ALDH1A1 (0.48) | GAAALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL28021082 | 0.75 | OGG1 (0.47) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL1387968 | 0.74 | GAA (0.42) | GAAALDH1A1NPSR1KDM4EHSD17B10 | |
| SCHEMBL1694924 | 0.73 | TDP1 (0.74) | GAAL3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL8857861 | 0.73 | ALDH1A1 (0.55) | GAAL3MBTL1ALDH1A1TDP1NPSR1 | |
| SCHEMBL11221531 | 0.73 | ALDH1A1 (0.58) | GAAL3MBTL1ALDH1A1TDP1NPSR1 | |
| SCHEMBL6463823 | 0.73 | PPARA (0.59) | GAANPSR1KDM4EHPGDHSD17B10 | |
| SCHEMBL5416139 | 0.73 | CYP1A2 (0.68) | GAAL3MBTL1ALDH1A1TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958914-B | 1-phenyl substituted heterocyclic derivatives and their use as prostaglandin D2 receptor modulators | ACTELION PHARMACEUTICALS LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-104428305-A | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators | ACTELION PHARMACEUTICALS LTD | 2015-03-18 | — | — | CN | disclosed |