Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997553 | 0.75 | GAA (0.44) | ALDH1A1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL11869391 | 0.72 | OGG1 (0.53) | OGG1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL22227971 | 0.72 | ALDH1A1 (0.66) | OGG1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL4211676 | 0.72 | SMN1; SMN2 (0.67) | ALDH1A1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL30602658 | 0.72 | ALDH1A1 (0.66) | OGG1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL6204339 | 0.70 | ALDH1A1 (0.49) | OGG1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL11547674 | 0.70 | ALDH1A1 (0.63) | OGG1ALDH1A1KDM4ELMNA | |
| SCHEMBL15518173 | 0.70 | OGG1 (0.62) | OGG1ALDH1A1POLBMAPTLMNA | |
| SCHEMBL9722109 | 0.70 | ALDH1A1 (0.72) | OGG1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL28904035 | 0.70 | ALDH1A1 (0.50) | OGG1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958914-B | 1-phenyl substituted heterocyclic derivatives and their use as prostaglandin D2 receptor modulators | ACTELION PHARMACEUTICALS LTD | 2015-05-27 | — | — | CN | disclosed |