Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542185 | 0.84 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28414837 | 0.78 | HTR2A (0.38) | MEN1KMT2AALDH1A1MAPT | |
| Formamide SCHEMBL28725518 | 0.78 | HTR2A (0.42) | LMNABLMMEN1KMT2AALDH1A1 | |
| SCHEMBL3696570 | 0.75 | ALDH1A1 (0.44) | LMNABLMALDH1A1MAPT | |
| SCHEMBL23183322 | 0.71 | EPHX2 (0.39) | LMNABLMMEN1KMT2A | |
| SCHEMBL17648648 | 0.71 | EPHX2 (0.39) | LMNABLMMEN1KMT2A | |
| SCHEMBL1325109 | 0.70 | THRB (0.38) | LMNABLMMAPT | |
| SCHEMBL15084239 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7134004 | 0.69 | LMNA (0.39) | LMNABLMALDH1A1MAPT | |
| SCHEMBL715619 | 0.69 | EPHX2 (0.38) | LMNABLMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104271576-A | Pyridopyrimidinone inhibitors of kinases | ABBVIE INC | 2015-01-07 | — | — | CN | disclosed |