Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623107 | 0.81 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10SYKNPC1 | |
| Hydrochloric Acid SCHEMBL1757952 | 0.80 | PRMT5 (0.42) | PRMT5ALDH1A1HSD17B10SYKNPC1 | |
| SCHEMBL6971634 | 0.80 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10SYKMAPK9 | |
| SCHEMBL260609 | 0.80 | ALDH1A1 (0.44) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL13860748 | 0.78 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10SYKMAPK9 | |
| SCHEMBL4326134 | 0.78 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10SYKMAPK9 | |
| SCHEMBL8592028 | 0.78 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10SYKMAPK9 | |
| SCHEMBL5474571 | 0.75 | LMNA (0.37) | PRMT5ALDH1A1HSD17B10SYKL3MBTL1 | |
| SCHEMBL5474570 | 0.75 | LMNA (0.37) | PRMT5ALDH1A1HSD17B10SYKL3MBTL1 | |
| SCHEMBL27595024 | 0.75 | PRMT5 (0.41) | PRMT5ALDH1A1HSD17B10SYKMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478828-A | 2-amino-7-substituted benzothiazole compound as well as preparation method and application thereof | ZHANGZHOU PIEN TZE HUANG PHARM | 2015-04-01 | — | — | CN | disclosed |