Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474570 | 1.00 | LMNA (0.37) | LMNAGAAL3MBTL1PRMT5ALDH1A1 | |
| SCHEMBL3623107 | 0.79 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10SYK | |
| Hydrochloric Acid SCHEMBL1757952 | 0.78 | PRMT5 (0.42) | PRMT5ALDH1A1HSD17B10SYK | |
| SCHEMBL30852522 | 0.76 | ALDH1A1 (0.38) | LMNAL3MBTL1PRMT5ALDH1A1HSD17B10 | |
| SCHEMBL27998630 | 0.75 | PRMT5 (0.43) | L3MBTL1PRMT5ALDH1A1HSD17B10SYK | |
| SCHEMBL6971634 | 0.74 | PRMT5 (0.43) | L3MBTL1PRMT5ALDH1A1HSD17B10SYK | |
| SCHEMBL260609 | 0.74 | ALDH1A1 (0.44) | LMNAL3MBTL1PRMT5ALDH1A1HSD17B10 | |
| SCHEMBL4326137 | 0.74 | ALDH1A1 (0.39) | L3MBTL1PRMT5ALDH1A1HSD17B10 | |
| SCHEMBL8592028 | 0.72 | PRMT5 (0.43) | L3MBTL1PRMT5ALDH1A1HSD17B10SYK | |
| SCHEMBL13860748 | 0.72 | PRMT5 (0.43) | LMNAL3MBTL1PRMT5ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060589-A1 | Inhibitors of protein arginine methyl transferases | BRISTOL-MYERS SQUIBB COMPANY | 2007-03-15 | — | — | US | disclosed |
| WO-2006069155-A2 | INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060589-A1 | Inhibitors of protein arginine methyl transferases | PRMT1, PRMT3, PRMT6 | LMNA 3814/4885GAA 3575/4885L3MBTL1 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.