Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747523 | 0.83 | HDAC3 (0.44) | — | |
| SCHEMBL16041339 | 0.81 | OGG1 (0.40) | ACACBOGG1NPC1RAB9AMEN1 | |
| SCHEMBL255667 | 0.81 | ACACB (0.52) | ACACBOGG1ALDH1A1NPC1RAB9A | |
| SCHEMBL20087479 | 0.81 | ALDH1A1 (0.48) | EPHX2NR1H4ALDH1A1NPC1RAB9A | |
| SCHEMBL14348621 | 0.79 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AHPGDPOLB | |
| SCHEMBL21350587 | 0.79 | KMT2A (0.43) | ACACBOGG1ALDH1A1NPC1RAB9A | |
| SCHEMBL28604460 | 0.78 | RBP4 (0.36) | ALDH1A1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL25207178 | 0.75 | MEN1 (0.42) | OGG1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2261328 | 0.74 | KCNN4 (0.44) | — | |
| SCHEMBL20289377 | 0.73 | TGM2 (0.54) | EPHX2NR1H4ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102834394-B | Bicyclic quinolone compounds, preparation and application thereof | KBP BIOSCIENCES CO LTD | 2015-03-25 | — | — | CN | disclosed |