Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111563 | 0.77 | SMN1; SMN2 (0.38) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL28019155 | 0.77 | ALDH1A1 (0.35) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL27969757 | 0.76 | SMN1; SMN2 (0.42) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL28000048 | 0.75 | LMNA (0.34) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL28000042 | 0.75 | ATM (0.35) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL16711263 | 0.68 | ALDH1A1 (0.44) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL16748755 | 0.68 | ALDH1A1 (0.47) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL3011426 | 0.66 | ALDH1A1 (0.45) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL16391280 | 0.66 | ALDH1A1 (0.45) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 | |
| SCHEMBL28231627 | 0.66 | ALDH1A1 (0.45) | LMNAPOLBSMN1; SMN2ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334557-A | Diacylglycerol acyltransferase 2 inhibitors | PFIZER | 2015-02-04 | — | — | CN | disclosed |