Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517898 | 0.82 | ALDH1A1 (0.33) | — | |
| SCHEMBL11595081 | 0.78 | MMP1 (0.30) | — | |
| SCHEMBL4836032 | 0.77 | HSD17B10 (0.48) | — | |
| SCHEMBL27993425 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL7092154 | 0.76 | GAA (0.52) | — | |
| SCHEMBL3189814 | 0.75 | TP53 (0.34) | — | |
| SCHEMBL9450866 | 0.75 | PSEN1 (0.30) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18660576 | 0.75 | PSEN1 (0.30) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8951866 | 0.74 | TSHR (0.50) | — | |
| SCHEMBL514631 | 0.73 | NPC1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379560-A | Benzamide derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |