Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315277 | 0.85 | LMNA (0.31) | SMN1; SMN2 | |
| SCHEMBL28000108 | 0.76 | PSEN1 (0.31) | — | |
| SCHEMBL4836032 | 0.76 | HSD17B10 (0.48) | ALDH1A1HSD17B10TDP1HTTSMN1; SMN2 | |
| SCHEMBL3617107 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL28055 | 0.74 | ENPP2 (0.39) | — | |
| SCHEMBL5923176 | 0.73 | HTR6 (0.48) | ALDH1A1HSD17B10TDP1HTTSMN1; SMN2 | |
| SCHEMBL2223680 | 0.73 | NPSR1 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23356361 | 0.71 | DRD1 (0.32) | — | |
| SCHEMBL160580 | 0.71 | PSIP1 (0.56) | ALDH1A1HSD17B10TDP1HTTSMN1; SMN2 | |
| SCHEMBL6764218 | 0.70 | PSEN1 (0.31) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379560-A | Benzamide derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |
| CN-104379568-A | Quinazolinedione derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |