Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18660576 | 1.00 | PSEN1 (0.30) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL971270 | 0.77 | LMNA (0.42) | — | |
| SCHEMBL28000108 | 0.75 | PSEN1 (0.31) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11221793 | 0.74 | PSIP1 (0.42) | — | |
| SCHEMBL5505800 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL1828201 | 0.73 | CA1 (0.47) | — | |
| SCHEMBL6764218 | 0.73 | PSEN1 (0.31) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10766553 | 0.73 | VCAM1 (0.46) | — | |
| SCHEMBL29119590 | 0.73 | CA12 (0.36) | — | |
| SCHEMBL6319405 | 0.73 | CA12 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537220-A1 | DIAZO COMPOUNDS, METHOD FOR PREPARING THEM, AND THEIR USE AS DYES. | HOECHST AG (DE) | 1993-04-21 | — | — | EP | disclosed |