Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27982978 | 0.79 | ACE (0.41) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL27863466 | 0.76 | OPRM1 (0.38) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL18999690 | 0.72 | KIF11 (0.40) | KMT2AOPRM1OPRD1OPRK1HSD17B3 | |
| SCHEMBL18100258 | 0.72 | OPRM1 (0.45) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| Nitrobenzene SCHEMBL28128310 | 0.69 | KMT2A (0.41) | KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL27863497 | 0.67 | SRD5A1 (0.40) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL28268229 | 0.67 | SLC6A2 (0.35) | KMT2AMEN1NAMPT | |
| SCHEMBL3807737 | 0.66 | GABRA1 (0.38) | OPRM1OPRD1OPRK1HSD17B3BRD4 | |
| SCHEMBL28268355 | 0.66 | HSD17B3 (0.34) | HSD17B3HTR2AHTR2CHTR2B | |
| SCHEMBL15778994 | 0.65 | SLC6A2 (0.40) | OPRM1OPRD1OPRK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245685-B | The production method of (acetylene-1,2-diyl) double (isobenzofuran-1,3-diketone) | 聂克斯姆化学有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-104245685-A | PROCESS FOR PRODUCING (ETHYNE-1,2-DIYL)BIS(ISOBENZOFURAN-1,3- DIONE) | NEXAM CHEMICAL AB | 2014-12-24 | — | — | CN | disclosed |