Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682006 | 1.00 | PNMT (0.50) | PNMTKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL16455000 | 0.84 | HTR2A (0.42) | KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL28001062 | 0.81 | LMNA (0.53) | KMT2ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL29337600 | 0.80 | MRGPRX4 (0.45) | KMT2ASMN1; SMN2AKT1CDC7DAPK3 | |
| SCHEMBL8607930 | 0.79 | SCN4A (0.58) | LMNAKCNH2SCN4A | |
| SCHEMBL8798650 | 0.78 | KDM4E (0.46) | KMT2ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL17186976 | 0.77 | KDM4E (0.43) | KMT2ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL9053577 | 0.76 | SCN4A (0.57) | LMNAKCNH2SCN4A | |
| SCHEMBL22379972 | 0.75 | SCN4A (0.48) | LMNAKCNH2AKT1CDC7DAPK3 | |
| SCHEMBL10701351 | 0.75 | KMT2A (0.56) | KMT2ASMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811424-A | CONTROL OF DOWNY MILDEW, LATE BLIGHT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |