Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283765 | 0.84 | HDAC4 (0.43) | HDAC4HDAC7HDAC5EGFRPDGFRB | |
| SCHEMBL29843820 | 0.74 | HDAC4 (0.37) | HDAC4HDAC7HDAC5EGFRP2RX4 | |
| SCHEMBL21250753 | 0.73 | PDGFRB (0.46) | HDAC4HDAC7HDAC5EGFRPDGFRB | |
| SCHEMBL27593684 | 0.73 | ALDH1A1 (0.36) | HDAC4HDAC7HDAC5KDM4EP2RX4 | |
| SCHEMBL28979084 | 0.73 | CASP1 (0.37) | HDAC4HDAC7HDAC5EGFRKDM4E | |
| Iodide SCHEMBL2347798 | 0.73 | HDAC4 (0.36) | HDAC4HDAC7HDAC5EGFRP2RX4 | |
| Iodide SCHEMBL2347792 | 0.73 | HDAC4 (0.36) | HDAC4HDAC7HDAC5EGFRP2RX4 | |
| SCHEMBL31324048 | 0.72 | PDGFRB (0.42) | HDAC4HDAC7HDAC5EGFRPDGFRB | |
| SCHEMBL28283868 | 0.72 | MTNR1A (0.40) | HDAC4HDAC7HDAC5EGFRKDM4E | |
| SCHEMBL29250274 | 0.70 | POLB (0.44) | HDAC4HDAC7HDAC5EGFRNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423839-A | Enzymatic hexose amination of lactose | 巴斯夫欧洲公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-111196817-B | Tricyclic compounds as BRPF1 inhibitors | 四川大学华西医院 | 2021-06-11 | — | — | CN | disclosed |
| CN-111196817-A | Tricyclic compounds as BRPF1 inhibitors | 四川大学华西医院 | 2020-05-26 | — | — | CN | disclosed |
| CN-102675897-B | Thiourea/urea aromatic amine dye, as well as preparation method and application thereof | UNIV SHAANXI NORMAL | 2015-04-29 | — | — | CN | disclosed |