Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478909 | 0.87 | KCNH2 (0.51) | CCR3KCNH2GPR119DRD2HTR2A | |
| SCHEMBL9030647 | 0.79 | SIGMAR1 (0.67) | KCNH2DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14100439 | 0.78 | KCNH2 (0.53) | CCR3KCNH2GPR119DRD2HTR2A | |
| SCHEMBL19658472 | 0.78 | KCNH2 (0.53) | KCNH2GPR119DRD2HTR2AHTR2C | |
| SCHEMBL19658477 | 0.77 | CCR5 (0.55) | DRD2SIGMAR1CCR5ALDH1A1 | |
| SCHEMBL4592218 | 0.77 | CHRM2 (0.64) | KCNH2GPR119DRD2HTR2AHTR2C | |
| SCHEMBL19658974 | 0.76 | DRD2 (0.54) | CCR3DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL17896801 | 0.76 | MAP4K4 (0.56) | CCR3KCNH2GPR119DRD2HTR2A | |
| SCHEMBL13173159 | 0.76 | KCNH2 (0.42) | CCR3KCNH2GPR119CCR5ALDH1A1 | |
| SCHEMBL402896 | 0.76 | CCR3 (0.49) | CCR3KCNH2GPR119MAP4K4CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396399-B | Nitrogenated aromatic 6-membered ring derivative, and pharmaceutical agent comprising same | DAIICHI SANKYO CO LTD | 2015-04-29 | — | — | CN | claimed |