Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914881 | 0.87 | LOXL2 (0.42) | LOXL2ALDH1A1HSD17B10CFTRKDM4E | |
| SCHEMBL28775528 | 0.81 | ALOX15 (0.33) | ALDH1A1HPGDALOX15 | |
| SCHEMBL27678389 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRHPGDLMNA | |
| SCHEMBL130031 | 0.78 | TSHR (0.44) | ALDH1A1HSD17B10CFTRKDM4EGAA | |
| SCHEMBL1196349 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CFTRKDM4EGAA | |
| SCHEMBL2551744 | 0.77 | TSHR (0.42) | ALDH1A1HSD17B10CFTRKDM4EGAA | |
| SCHEMBL21268184 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CFTRKDM4EGAA | |
| SCHEMBL1128064 | 0.75 | ALDH1A1 (0.62) | LOXL2ALDH1A1HSD17B10CFTRKDM4E | |
| SCHEMBL1978589 | 0.75 | LMNA (0.55) | ALDH1A1HSD17B10CFTRKDM4EGAA | |
| Hydrochloric Acid SCHEMBL25289042 | 0.74 | ALDH1A1 (0.60) | LOXL2ALDH1A1HSD17B10CFTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583177-B | Aryl alkyl amines as calcium-sensing receptor regulator | 卢平亚特兰蒂斯控股有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-104583177-A | Arylalkylamine compounds as calcium sensing receptor modulators | LUPIN LTD | 2015-04-29 | — | — | CN | disclosed |
| CN-1926112-A | Novel difluoroethoxy-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors | ALTANA PHARMA AG (DE) | 2007-03-07 | — | — | CN | disclosed |