Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1423573 | 0.88 | KEAP1 (0.60) | KEAP1LMNAPGRPTGS2PTGS1 | |
| SCHEMBL873846 | 0.84 | KEAP1 (0.75) | KEAP1LMNAPGRPTGS2KIF11 | |
| SCHEMBL56693 | 0.80 | KEAP1 (1.00) | KEAP1LMNAPGRPTGS2KIF11 | |
| SCHEMBL18427042 | 0.78 | KEAP1 (0.64) | KEAP1LMNAPGRPTGS2KIF11 | |
| Hydrochloric Acid SCHEMBL27365433 | 0.78 | KEAP1 (0.95) | KEAP1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11512295 | 0.78 | KEAP1 (0.95) | KEAP1LMNACYP1A2CYP2D6CYP2C9 | |
| Hydrogen Sulfide SCHEMBL27698561 | 0.78 | KEAP1 (0.95) | KEAP1LMNACYP1A2CYP2D6CYP2C9 | |
| Fluoride SCHEMBL28258745 | 0.78 | KEAP1 (0.95) | KEAP1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL21092440 | 0.76 | KIF11 (0.69) | KEAP1USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL31041151 | 0.75 | KIF11 (0.79) | KEAP1LMNACYP2C9CLK4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100263306-A1 | ROOM WITH TWO COUNTER-RESISTANT INSECTICIDAL OBJECTS | VESTERGAARD FRANDSEN SA (CH) | 2010-10-21 | — | — | US | disclosed |
| EP-2219444-A2 | ROOM WITH TWO COUNTER-RESISTANT INSECTICIDAL OBJECTS | Vestergaard Frandsen SA (CH) | 2010-08-25 | — | — | EP | disclosed |
| US-20100119720-A1 | PROCESS FOR INSECTICIDAL IMPREGNATION OF A FABRIC OR NETTING OR OTHER KIND OF NON-LIVING MATERIAL | VESTERGAARD FRANDSEN SA (CH) | 2010-05-13 | — | — | US | disclosed |
| EP-2141987-A1 | PROCESS FOR INSECTICIDAL IMPREGNATION OF A FABRIC OR NETTING OR OTHER KIND OF NON-LIVING MATERIAL | Vestergaard Frandsen SA (CH) | 2010-01-13 | — | — | EP | disclosed |
| WO-2009059603-A1 | ROOM WITH TWO COUNTER-RESISTANT INSECTICIDAL OBJECTS | VESTERGAARD FRANDSEN SA (CH) | 2009-05-14 | — | — | WO | disclosed |
| WO-2009059607-A2 | ROOM WITH TWO COUNTER-RESISTANT INSECTICIDAL OBJECTS | VESTERGAARD FRANDSEN SA (CH) | 2009-05-14 | — | — | WO | disclosed |
| WO-2008122287-A1 | PROCESS FOR INSECTICIDAL IMPREGNATION OF A FABRIC OR NETTING OR OTHER KIND OF NON-LIVING MATERIAL | VESTERGAARD FRANDSEN SA (CH) | 2008-10-16 | — | — | WO | disclosed |
| CN-101247722-A | Biphenyl-N- (4-pyridyl) methylsulfonamides | BASF AG (DE) | 2008-08-20 | — | — | CN | disclosed |
| US-20080161187-A1 | Controlling phytopathogenic harmful fungi and harmful arthropodes; combating arthropodal pestsprotecting crops, seeds and non-living materials from infestation by arthropodal pests; insecticides, pesticides, fungicides; miticides; agriculture; veterinary medicine | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161187-A1 | Controlling phytopathogenic harmful fungi and harmful arthropodes; combating arthropodal pestsprotecting crops, seeds and non-living materials from infestation by arthropodal pests; insecticides, pesticides, fungicides; miticides; agriculture; veterinary medicine | PTPN21, PTPN1, PTPN14 | KEAP1 395/4885CYP17A1 1107/4885USP2 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.