Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840 | 0.75 | PDPK1 (0.51) | PNP | |
| SCHEMBL30150749 | 0.75 | PDPK1 (0.51) | PNP | |
| SCHEMBL4455866 | 0.69 | PI4KA (0.38) | PNPNOS3NOS1NOS2 | |
| SCHEMBL6266584 | 0.69 | PNP (0.56) | PNP | |
| SCHEMBL1808631 | 0.68 | ADORA3 (0.34) | — | |
| SCHEMBL29060874 | 0.67 | PNP (0.40) | PNP | |
| SCHEMBL3396382 | 0.67 | PNP (0.52) | PNP | |
| SCHEMBL11413670 | 0.67 | CASP1 (0.54) | NOS3NOS1NOS2PDE8B | |
| SCHEMBL27734016 | 0.66 | ADORA3 (0.35) | — | |
| SCHEMBL5742923 | 0.65 | CDK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | disclosed |